Endocrine Abstracts

Background: Cystic Fibrosis related diabetes affects 40-50% of adults with cystic fibrosis (CF). This can significantly affect pulmonary function and life expectancy. Kaftrio (Ivakaftor, tezacaftor and elexacaftor) has recently been licensed for use in CF. Previous data highlight that glucose regulation may be altered on commencing this treatment.Methods: Eight children and young people (CYP), aged 14 (12-15) years, who were diagnosed with CFRD aged 12.8...

Introduction: The COVID-19 pandemic prevented face-to-face school diabetes training in 2020/2021 at Birmingham Women’s and Children’s Hospital. Moving school training online was the only viable option to ensure children with type 1 diabetes could attend school.Objectives: 1. Develop an online school training package with competency assessment for all diabetes devices 2. Audit the number of staff competent and the cost and acceptability of the t...

Introduction: Racism is a fundamental determinant of health, described by Prof Kevin Fenton (PHE) as a "wicked problem"- a complex problem highly resistant to solutions. The amplification of the voice of black lives matter” and disproportionate number of deaths from Covid-19 in Black and Asian people has re-focussed attention on racial health inequalities. Structural racism and unconscious bias is present throughout medicine. The National Paediatric Diabetes Audit...

Diabetic Ketoacidosis (DKA) is a significant complication of paediatric diabetes, the effective management of which relies on meticulous calculations, and timely decision making in response to changing physiology. A previous regional audit in South West England has shown that compliance with national guidelines is highly variable, and errors in calculations such as fluid rates are common. Fluid management in paediatric DKA is a subject of ongoing debate and changing guidance. ...

Introduction: Neonatal diabetes (ND) usually presents before 6 months of age and 50% of cases are transient and 50% permanent with more than 20 known genetic causes. Early recognition and urgent genetic testing are important to enable appropriate, precise treatment. Mutations in KCNJ11 cause ND responsive to glibenclamide, alleviating the need for insulin administration, but there are limited reports of early successful transition.Case: This inf...

Introduction: Structured education is an integral part of type one diabetes care for children and young people and their families, delivered at diagnosis. There is currently no validated curriculum or outcome measures of diabetes education in the UK. We evaluated the outcome of using the diabetes education app (deapp), using flipped learning against historical practice, to determine if it conferred any benefit in our single centre.Methods: Two cohorts of...

Background: Children and young people (CYPwD) with a persistent high HbA1c are at greater risk of developmental and long-term complications. Diabetes services across the England & Wales are mandated to have a ‘high HbA1c’ policy by the Best Practice Tariff quality standards, to improve health outcomes. Aim: To evaluate the Birmingham Women’s and Children’s (BWC) Diabetes Team ‘High HbA1c Policy’ from 2016 – 2019.</p...

Background: Our department cares for 273 children with type 1 diabetes (T1DM). All T1DM patients are issued with an uploadable glucose meter from diagnosis. 101 patients (37%) use insulin pump therapy and 126 (46%) use a continuous glucose monitoring device. Anecdotally we noted many patients were not uploading their data prior to coming to clinic. This contributed to reduced patient flow through diabetes clinics and also to reduced patient and carer engagement with their diab...

Background: At the beginning of the first Covid 19 lockdown the team realized the need for an innovative way of having contact with young people. Virtual sessions could do this? We also needed to meet young person’s wishes.Objectives: -For the activity to be fun. -Improve carbohydrate counting, knowledge, expertise and confidence -Give young people skills to be independent with their carb counting skills...