Searchable abstracts of presentations at key conferences in endocrinology
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48th Meeting of the British Society for Paediatric Endocrinology and Diabetes

Online, Virtual
24 Nov 2021 - 26 Nov 2021

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Oral Communications

Oral Communications 9

ea0078OC9.1 | Oral Communications 9 | BSPED2021

Variability in the diagnosis of growth hormone deficiency using dynamic tests. Time for robust pre-test criteria?

Zilber Eva , Cramer Rebecca , Crowne Elizabeth , Ryan Fiona , Daskas Nikolaos

Background: Insulin tolerance test (ITT) is the gold-standard investigation in children with suspected growth hormone deficiency (GHD). Despite their benefits, ITTs are resource intensive, potentially dangerous and can result in unnecessary treatment due to false positive results in children that are at low risk for GHD.Methods: Retrospective analysis of all paediatric patients undergoing an ITT in two tertiary hospitals in the UK (centre A between 2017-...

ea0078OC9.2 | Oral Communications 9 | BSPED2021

Sex steroid priming for growth hormone stimulation testing – a systematic review

Duncan Gregor , Mitchell Rod

Background: Growth hormone stimulation testing (GHST) is used to diagnose growth hormone deficiency (GHD) in children. Given that sex steroids impact on anterior pituitary function, there is concern around the efficacy of GH stimulation testing in pre/peripubertal children, where sex steroid levels are low. Sex steroid priming prior to GH stimulation testing is thought to improve test efficacy in these children, however evidence to support its use in clinical practice is limit...

ea0078OC9.3 | Oral Communications 9 | BSPED2021

Investigating paediatric weight management apps

Ayamad Sithara , Mohebi Mustafa , Sarathchandra Nichola Rowena , Shah Pratik , Desai Ashish , Gevers Evelien , Peh Gin , Ford-Adams Martha , Chan Li

Background: Childhood obesity is the single most pressing public health emergency of the 21st century. The prevalence has increased at alarming rates and globally over 41 million children under 5 years of age are classified as overweight/obese. Overweight and obese children are likely to stay obese as adults and develop multi-morbidities including type 2 diabetes, cancer, non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease at an earlier age. The ava...

ea0078OC9.4 | Oral Communications 9 | BSPED2021

Changes in trends in Short Synacthen Test use over a decade - a single centre experience

Ross Callum , Nicole Craig Jessica , Hariprasad Anu-Sree , Auckland Isobel , Colyer Sharon , Elder Charlotte

Background: The Short Synacthen Test (SST) is the most popular test of adrenal insufficiency (AI) worldwide. The current SST protocol at Sheffield Children’s Hospital (SCH) recommends measurement of serum cortisol at baseline, then 30- and 60-minutes post stimulation. A peak cortisol of >429nmol/l constitutes a pass. Our practise has evolved to consider results between 350 and 429nmol/l as “borderline” and these patients may be treated with stress dosing ste...

ea0078OC9.5 | Oral Communications 9 | BSPED2021

Variability of advice and education for steroid sick day dosing in Duchenne Muscular Dystrophy: Results of a UK patient survey

Thakrar S , Cheung MS , Johnson A , Katugampola H , Manzur A , Muntoni F , Mushtaq T , Turner C , Wood C , Guglieri M , Wong SC

Introduction: The use of long-term oral corticosteroids in DMD leads to secondary adrenal insufficiency. The 2018 international care consensus recognizes this important issue and recommends emergency plans to be in place. Aim: This online UK-wide patient survey aims to determine the advice/education given for emergency stress dose plans and the impact of the COVID-19 pandemic in corticosteroid-treated young people with DMD. Methods...

ea0078OC9.6 | Oral Communications 9 | BSPED2021

’Think Adrenal’: An innovative trust-wide safety and education programme designed for the care of patients with adrenal insufficiency

Tollerfield Sally , Atterbury Abigail , Wadey Hannah , Katugampola Harshini

Over 700 patients with known adrenal insufficiency are treated across the trust. Whilst unwell or fasting for a procedure, these patients potentially risk suffering an adrenal crisis. A flagging system has already been implemented on the electronic patient records (EPR) which identifies patients who are ‘on replacement Hydrocortisone’. Following an inpatient adrenal crisis which could have been more optimally managed, we sought to highlight care of this vulnerable co...