ea0041ep569 | Diabetes therapy | ECE2016
Schwetz Verena
, Eisner Florian
, Schilcher Gernot
, Eller Kathrin
, Plank Johannes
, Lind Alice
, Pieber Thomas R
, Mader Julia K
, Eller Philipp
Introduction: In metformin-associated lactic acidosis with renal dysfunction inhibition of hepatic gluconeogenesis by drug accumulation may aggravate fasting induced-ketoacidosis. We report the occurrence of metformin-associated lactic acidosis with concurrent euglycemic ketoacidosis in three patients with renal failure.Cases: The first patient was a 79-year-old woman who suffered from chronic kidney disease stage IIIa after traumatic uninephrectomy, and...