ea0037ep342 | Diabetes (pathiophysiology & epitemiology) | ECE2015
Demir Tevfik
, Onay Huseyin
, Savage David B
, Kuruuzum Ayse Kubat
, Erdeve Senay Savas
, Altay Canan
, Ozen Samim
, Demir Leyla
, Cavdar Umit
, Akinci Baris
Introduction: Familial partial lipodystrophy (FPL) is a rare genetic disorder characterised by a selective lack of subcutaneous fat that is associated with insulin resistance and diabetes. FPL has been reported to be caused by mutations in the peroxisome proliferator activator receptor-γ (PPARG) gene, which encodes a key transcription factor that regulates adipocyte differentiation and insulin sensitivity.Material and methods: The objective of this ...