Endocrine Abstracts

Swyer syndrome (46XY karyotype) is a rare disorder of sexual development. Patients phenotypically appear female with normal external genitalia and vagina. 14 year old girl is evaluated for primary amenorrhea. She is 176 cm and weighs 61 kg (BMI=19.7 kg/m2) – she has had significant growth for the past year. The girl has a vagina with 7 cm in length, there is no terminal hair or breast development (Tanner I). MRI of pelvis shows uterine hypoplasia, ovary agenesi...

Background: Phase angle (PA) is defined as the angular displacement between the current and voltage waveforms due to capacitor interference, measured in degrees or radians. [1] The fat-free mass (FFM) is made up of water and electrolytes and is characterized by a low impedance, while the FM (fat mass) is water-free and, therefore, with a high impedance. The larger the FM, the higher the resistance, and this parameter affects the PA. Body mass index (BMI) is the most widely use...

A 41 year old male patient presented to the endocrinology unit due to recurrent long bone fractures and teeth decay. His past medical history was nonsignificant for any chronic disease. He was a child of consanguineous marriage; his father and mother were first degree cousins. There were no other family members with similar phenotype or history of recurrent fractures He was 154 cm in height and weighed 58 kg. The arm span was 139 cm. Upper to lower segment ratio was 1.16. He h...

A 42 year old male patient was admitted to the gastroenterology unit in due to severe abdominal pain and vomiting. He denied any chronic illness and drug usage. His family history was nonsignificant for any endocrine disease. Based on biochemical studies (lipase 2280 U/l, calcium 15.0 mg/dl, phosphorus 1.7 mg/dl amylase 631 U/l, creatinine 1.16 mg/dl, ALP 735 U/l) severe hypercalcemia induced acute pancreatitis was the diagnosis. 25 OH vitamin D was 5 ng/ml and parathyroid hor...