Searchable abstracts of presentations at key conferences in endocrinology

ea0063p323 | Reproductive Endocrinology 1 | ECE2019

Effects of fludioxonil on cardiac differentiation of mouse embryonic stem cells

Ko Eul-Bee , Hwang Kyung-A , Choi Kyung-Chul

Fludioxonil, a phenylpyrrole fungicide, is extensively used to protect particularly fruits and vegetables from fungi. On the contrary, it has been reported that fludioxonil caused low weight birth in rats at parentally toxic doses. However, its developmental toxicity on cardiac differentiation has not yet been understood. In the present study, the early developmental toxicity of fludioxonil on the cardiac differentiation of mouse embryonic stem cells (mESCs) was evaluated. Fir...