Searchable abstracts of presentations at key conferences in endocrinology

ea0090p82 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Testosterone serum levels predict the severity of metabolic dysfunction associated fatty liver disease (MAFLD) in hypogonadal men

Santi Daniele , Spaggiari Giorgia , Nascimbeni Fabio , Lugari Simonetta , Felicani Cristina , Dalla Valentina Leonardo , Ahmad Ali , Raffaele Michele Granata Antonio , Andreone Pietro , Simoni Manuela

Background: Metabolic dysfunction associated fatty liver disease (MAFLD), the leading cause of chronic liver disease, is defined as the presence of hepatic steatosis and metabolic risk factors. Both testosterone and estradiol seem to have a pivotal role in hepatic lipid homeostasis, although underlying mechanisms are still unclear. Low testosterone serum levels result independently associated with MAFLD, but no studies so far evaluated MAFLD prevalence and severity in hypogona...

ea010228 | Reproductive Endocrinology | EYES2024

Testosterone serum levels predict the severity of metabolic dysfunction-associated steatotic liver disease (MASLD) in hypogonadal men

Dalla Valentina Leonardo , Spaggiari Giorgia , Nascimbeni Fabio , Lugari Simonetta , Feliciani Cristina , Ahmad Ali , R. M. Granata Antonio , Andreone Pietro , Simoni Manuela , Santi Daniele

Introduction: Metabolic dysfunction-associated steatotic liver disease (MASLD) is defined by the presence of hepatic steatosis and metabolic risk factors. Both testosterone and estradiol play pivotal roles in hepatic lipid homeostasis, though the underlying mechanisms remain unclear. Low serum testosterone levels are independently associated with MASLD. However, no studies have previously evaluated the prevalence and severity of MASLD in hypogonadal men. <p class="abstext"...