ea0029p1630 | Thyroid (non-cancer) | ICEECE2012
Antonelli A.
, Ferrari S.
, Sellari-Franeschini S.
, Corrado A.
, Mancusi C.
, Ferrini M.
, Ferrannini E.
, Fallahi P.
Introduction: No study has evaluated the effect of cytokines on the prototype beta chemokine (C-C motif) ligand (CCL)2 in GravesÂ’ ophthalmopathy (GO), nor of peroxisome proliferator-activated receptor (PPAR)alpha activation on this chemokine secretion in fibroblasts or preadipocytes in GO.Design and methods: We have tested the interferon (IFN)gamma and tumor necrosis factor (TNF)alpha effect on CCL2, and for comparison on the prototype alpha chemoki...