Endocrine Abstracts

Introduction: The role of surgery to resect the primary lesion in incurable metastatic small intestinal (SI-NET) and pancreatic neuroendocrine tumours (P-NET) remains controversial. Recent evidence suggests that palliative surgery may increase survival even in asymptomatic patients with non-functioning tumours. The present study investigated the value of palliative resection of the primary tumour in SI-NET and P-NET by systematic literature review and meta-analysis.<p clas...

Background: Transplantation for cancer indications is evolving rapidly in UK and Ireland. Liver transplantation [LT] for unresectable neuroendocrine tumour liver metastases [NET LM] is one of three new cancer indications. It has the potential to significantly improve survival outcomes however, transplant benefit has likely been achieved only by highly experienced Centre(s). Since eligible patients for transplantation also have excellent prognosis with standard management, care...

Introduction: Appendiceal NENs are usually diagnosed incidentally on histology following an appendicectomy. They include carcinoid tumours (appendiceal neuroendocrine tumours, NETs) and GCC. GCC neoplasms are able to transform to an adenocarcinoma phenotype. There are several important criteria to review when deciding on the treatment and follow up for appendiceal NENs, in particular when to offer further surgery to patients.Aim: To assess whether the ma...