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ea0050p321 | Obesity and Metabolism | SFEBES2017

Rectal and oral administration of L-Phenylalanine supresses food intake and modulates neuronal activation in appetite-regulating brain regions in rodents

Norton Mariana , Cao Ye , Amarsi Risha , Freitas Isabel Fernandes , Alamshah Amin , Murphy Kevin G

High protein diets are highly satiating but hard to maintain. By understanding the mechanisms underlying these effects we may be able to identify new anti-obesity therapies. Protein is broken-down into amino acids in the gut which are detected by a series of nutrient sensors. The calcium sensing receptor (CaSR) is primarily activated by calcium ions, but is positively allosterically modulated by aromatic amino acids, especially L-phenylalanine. Sti...

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ea0050p321 | Obesity and Metabolism | SFEBES2017

Rectal and oral administration of L-Phenylalanine supresses food intake and modulates neuronal activation in appetite-regulating brain regions in rodents

Norton Mariana , Cao Ye , Amarsi Risha , Freitas Isabel Fernandes , Alamshah Amin , Murphy Kevin G

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Endocrine Abstracts

Rectal and oral administration of L-Phenylalanine supresses food intake and modulates neuronal activation in appetite-regulating brain regions in rodents

Rectal and oral administration of L-Phenylalanine supresses food intake and modulates neuronal activation in appetite-regulating brain regions in rodents

BiosciAbstracts