ea0084op-01-06 | Oral Session 1: Topic Highlights | ETA2022
Lasolle Helene
, Gillotay Pierre
, Ceolin Lucieli
, Aganahi Benilda
, Malta Letro Kizys Marina
, Luiza Maia Ana
, Costagliola Sabine
, Romitti Mirian
Introduction: Due to their remarkable self-organizing structures and functional properties, organoid has become a powerful tool to model diseases in a dish. The use of organoids in cancer research emerged to better understand tumor behavior. Originally, adult stem cells (aSC)-derived organoids were derived from primary tumors while recent studies have reported the generation of cancer models arising from healthy cells by controlling oncogene expression. SC-derived ...