ea0035p1124 | Thyroid Cancer | ECE2014
Maciag Monika
, Kubiak Anna
, Swierniak Michal
, Dymecka Kinga
, Kolanowska Monika
, Koperski Lukasz
, Gornicka Barbara
, Stachlewska Elzbieta
, Jazdzewski Krystian
Introduction: Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy where alterations in the RET/PTCRASBRAF signaling pathway and deregulation of microRNA (miRNA) expression are suggested to be major mechanism of pathogenesis. MicroRNAs are small non-coding RNA molecules that recognize specific sequences in 3′UTR of target gene and prevent from its translation. Our recent deep sequencing studies of thyroid tissue transcriptome revealed a put...