Searchable abstracts of presentations at key conferences in endocrinology

ea0016p39 | Adrenal | ECE2008

Impaired endothelial morphology and function in patients with subclinical Cushing's syndrome due to single adrenocortical adenomas

Androulakis Ioannis , Kollias Georgios , Markou Athina , Gouli Aggeliki , Anagnostou Tilemachos , Stamatelopoulos Kimon , Papamichael Christos , Piaditis Georgios , Kaltsas Gregory

Background: Subclinical CushingÂ’s syndrome (SCS) due to incidentally discovered adrenal adenomas (AI) has been associated with increased prevalence of hypertension, obesity, and impaired glucose tolerance which are established risk factors for cardiovascular morbidity. Although functional and morphological (structural) changes of endothelium have been correlated with cardiovascular morbidity this has not been looked into detail in patients with adrenal incidentalomas....

ea0014p487 | (1) | ECE2007

Study of aldosterone secretion in patients with essential hypertension using a modified suppression test

Gouli Aggeliki , Androulakis Ioannis , Markou Athina , Ragkou Despoina , Dimitriou Konstantina , Stathopoulou Alexandra , Anagnostou Tilemachos , Kondyli Georgia , Piaditis George

Background: The renin-angiotensin system is important for blood pressure control. Screening and diagnostic tests used so far to diagnose patients with aldosterone related hypertension does not take into consideration the stimulating ACTH effect on aldosterone secretion.Objective: To assess the role of aldosterone in essential hypertension using a modified suppression test, performed under suppressed ACTH levels.Subjects and methods...

ea0014p76 | (1) | ECE2007

The role of stress related aldosterone secretion in essential hypertension

Markou Athina , Androulakis Ioannis , Gouli Aggeliki , Dimitriou Kostantina , Zacharoulis Achilleas , Papadopoulos Kostantinos , Barlogiannis Theodoros , Chariatis Evangelos , Halapas Antony , Kourlaba Eleni , Ragkou Despoina , Kondyli Georgia , Piaditis George

Introduction: Approximately 90% of the hypertensive population is characterized as having essential hypertension. Apart from renin and K+, ACTH plays an important role in aldosterone secretion, being a potent stimulant under situations of stress. Up to date, the association between stress and aldosterone-related hypertension has not been studied and that is the aim of our study.Methods: 36 hypertensive patients and 14 matched for age and sex c...

ea0014p157 | (1) | ECE2007

Prevalence of autonomous cortisol and aldosterone secretion in patients with a single benign cortical adrenal adenoma after modification of the diagnostic tests

Piaditis George , Kaltsas Gregory , Kounadi Theodora , Markou Athina , Mazarakis Nikos , Gouli Aggeliki , Makras Polyzois , Papadogias Dimitrios , Dimitriou Kostantina , Stathopoulou Alexandra , Kossyvakis Kostantinos , Despoina Ragkou , Kyriakos Vamvakidis , Zografos George , Kontogiorgos George , Chrousos George

Background: The normal cut-offs of screening and diagnostic tests for autonomous aldosterone (AAS) and cortisol (ACS) secretion are poorly defined, mainly due to the presence of adrenal adenomas among those who have served as controls and the stimulating effect of ACTH on aldosterone secretion.Methods: We investigated cortisol and aldosterone secretion in 151 patients with benign cortical adrenal adenomas (BCAA) and in 119 healthy controls with a normal ...