ea0020p577 | Neuroendocrinology, Pituitary and Behaviour | ECE2009
Gray Megan
, Bingham Brenda
, Viau Victor
The dampening of hypothalamicpituitaryadrenal (HPA) axis responses to a repeated stress is termed HPA habituation. We investigated here the effects of two commonly used repeated restraint stress paradigms, in which rats are exposed either to 10 episodes of 0.5 h restraint or 5 episodes of 3 h restraint. We compared ACTH, corticosterone, and testosterone responses, as well as corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) mRNA levels within bra...