Searchable abstracts of presentations at key conferences in endocrinology

ea0011s75 | Green over-the-counter endocrinology | ECE2006

Regulation of steroid receptor expression and proliferation in prostate cancer by genistein and other flavonoids

Bektic J , Guggenberger R , Schäfer G , Bartsch G , Klocker H

A diet rich in phytoestrogens such as flavonoids has been attributed as one of the reasons for the low incidence of prostate cancer in Asia as opposed to Western countries with a diet rich in fat and meat and the highest incidences of this cancer. In many cellular models of prostate cancer these substances, the prototype of which is genistein, inhibit cell proliferation and cell cycle progression and enhance the rate of apoptosis. The molecular mechanisms involve modulation of...