Endocrine Abstracts

Introduction: Several studies have investigated a possible action of vitamin D metabolites on different lipid fractions but the possible mechanism by which they could act remain unknown, with varying results in observational and intervention studies.Objective: To study the relation between vitamin D levels and lipids levels.Methods: We undertook a population-based cohort study in Spain. At baseline (1996–1998), 1226 subjects w...

Background and aims: To assess the relationship between 25-hydroxyvitaminD levels and prevalence and incidence of metabolic syndrome.Methods: We undertook a population-based cohort study in Spain. At baseline (1996–1998), 1226 subjects were evaluated. Follow-up visits were performed in 2002–2004 and 2005–2007. At baseline and follow-up, participants underwent an interview and a standardized clinical examination with an oral glucose toleran...

Background and aims: To assess the relationship between obesity and the incidence of hypovitaminosis D and investigate the relationship between 25-hydroxyvitamin D levels and incidence of obesity.Methods: We undertook a population-based cohort study in Spain. At baseline (1996–1998), 1226 subjects were evaluated. Follow-up visits were performed in 2002–2004 and 2005–2007. At baseline and follow-up, participants underwent an interview and a...

Results: Main clinical, analytical and polygraphic data: 58.1±6.4 years, body mass index 32.4±5.4 kg/m2, 70.4% female, HbA1c 8.0±1.9%, AIH 27.4 events/hour (in the range of severe sleep apnea and hypoapnea index), and CT90% 32.9%. Nocturnal concentration of urine total metanephrines were higher than diurnal levels (226±12 vs 98±13 μg/l; P=0.085). In addition, its nocturnal concentration was significantly associated, in a positi...