Searchable abstracts of presentations at key conferences in endocrinology

ea0020oc1.3 | Endocrine Tumours | ECE2009

131I-Iodometomidate radiotherapy for metastatic adrenocortical carcinoma: first clinical experience

Hahner Stefanie , Kreissl Michael , Fassnacht Martin , Johanssen Sarah , Haenscheid Heribert , Reiners Christoph , Allolio Bruno , Schirbel Andreas

Subject: Treatment options for adrenocortical carcinoma (ACC) are still unsatisfactory. We could recently demonstrate that several patients with ACC exhibit a high and specific uptake of 123I-Iodometomidate (123I-IMTO). Therefore, we investigated if 131I-IMTO holds potential for radiotherapy in ACC.Methods: Dosimetry with 40 MBq I-131-IMTO was performed over 5 days in 7 patients and calculated activities were administered on a compassionate use basis in ...