ea0049gp143 | Male Reproduction and Endocrine Disruptors | ECE2017
Munier Mathilde
, Louvigne Mathilde
, Rudelle Helene
, Gourdin Louis
, Briet Claire
, Henrion Daniel
, Chabbert Marie
, Coutant Regis
, Rodien Patrice
Metabolic diseases (type 2 diabetes (T2D) and obesity) prevalence is increasing in the world. This is partly related to a change in lifestyle with an increase of caloric intake and a decrease of physical activity. Environmental causes are also involved among them exposure to bisphenol A (BPA). The mode of action of the latter is unknown. Beyond a suggesting effect relayed by nuclear receptors, we propose that BPA can act by modulating the functionality of G protein-coupled rec...