Searchable abstracts of presentations at key conferences in endocrinology

ea0022p402 | Endocrine tumours &amp; neoplasia (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

High prevalence of dopamine excess in patients with head and neck paragangliomas

Horst-Schrivers Anouk van der , Osinga Thamara , Kema Ido , Dullaart Robin

Objective: We determined the prevalence of abnormal secretion of dopamine and other catecholamines in relation to clinical symptoms in patients with head and neck paragangliomas (PGL). The association of catecholamine production with nuclear imaging was also assessed.Methods: Thirty-six consecutive patients with head and neck PGLs, who were referred for follow-up and/or treatment between 1993 and 2009, were included. Clinical symptoms, dopamine excess (u...

ea0084ps3-15-135 | Thyroid Cancer Diagnosis & Treatment | ETA2022

Clinical relevance of lower titer thyroglobulin (TG) autoantibodies in patients with differentiated thyroid carcinoma

Dekker Bernadette , van der Horst-Schrivers Anouk , Brouwers A.H. , Shuford Chris , Kema Ido , Muller Kobold Anneke , Links Thera

Objectives: Thyroglobulin (Tg) is an established tumor marker for differentiated thyroid carcinoma (DTC) patients. However, Tg immunoassays can be subject to autoantibody (TgAb) interference resulting in incorrect Tg values. Tg measurement with liquid chromatography-tandem mass spectrometry (LC-MS/MS) could be promising in patients with TgAbs. In this study, we compared a Tg immunoradiometric assay (Tg-IRMA) and a Tg-LC-MS/MS analytically in the presence of TgAbs. Furthermore,...

ea0041gp152 | Pituitary - Clinical | ECE2016

Effects of hydrocortisone substitution on blood pressure – results from an RCT

Buning Jorien Werumeus , van Faassen Martijn , Brummelman Pauline , Dullaart Robin P F , van den Berg Gerrit , van der Klauw Melanie M , Kerstens Michiel N , Kobold Anneke C Muller , Kema Ido P , Wolffenbuttel Bruce H R , van Beek Andre P

Background: Patients with secondary adrenal insufficiency show increased risk of cardiovascular disease. Higher doses of glucocorticoid replacement are related to an unfavourable metabolic profile. In the absence of randomized controlled trials assessing the effect of hydrocortisone dose on haemodynamics and blood pressure regulation, we determined effects of a higher vs a lower glucocorticoid replacement dose on blood pressure, the renin-angiotensin-aldosterone system (RAAS) ...