Endocrine Abstracts

Case history: We present the case of a 72-year-old lady who presented to the surgical team with sudden onset abdominal (flank) pain. On initial assessment, she was significantly hypertensive (213/110 mmHg) and tachycardic (pulse 98 bpm) but afebrile. She was not on any anticoagulation. On physical examination, her abdomen was tender with mild guarding and retroperitoneal tenderness.Investigations: Admission blood tests showed a normal haemoglobin (149 g/...

Objectives: Investigate the effect of using moderate intensity activity between meals to lower hyperglycaemia on glucose metrics in children and young people with type 1 diabetes (CYPD).Design & Methods: Retrospective data from CYPD attending a continuous glucose monitoring (CGM) education programme at a tertiary centre between 2019 and 2022 were analysed. CYPD were taught to use moderate intensity activity to lower ...

Development of the fetal hypothalamic-pituitary-adrenal (HPA) axis is important for normal maturation of the fetus and the timing of parturition. In hypothyroid fetuses, gestational length may be prolonged and maturational processes delayed, although the role of the HPA axis is unknown. This study investigated the effects of hypothyroidism before birth on the structure and function of the anterior pituitary and adrenal glands in fetal sheep near term.All...