Endocrine Abstracts

Background and aims: Diabetic foot ulcers are a common problem and result in lower extremity amputations. Research on the prevalence of diabetic foot syndrome (DFS), food ulcers, and high amputations reflects the state of diabetic aid.Materials and methods: The data from the Moscow Region DM register on the detectability of DFS, the number of high amputations, the presence of late complications that enable the development of ulcer defects – diabetic...

Objective: investigate the assosiation between presence of sarcopenia and type 2 diabetes mellitus (T2DM).Methods: The study included 138 women over 60 years old (Me 72[67;78] years) (76 patients with T2DM). Patients were examined with evaluation of muscle mass, muscle strength and muscle function. Muscle strength was measured with carpal dynamometry, muscle function was evaluated with short physical performance battery tests. Skeletal muscle mass index ...

Material and methods: Data for 124 554 DM patients is contained in the DM register of Moscow region (MR) for 2004. Mortality is evaluated yearly.Results: Mortality as result of T1D was 1.92, and of T2D – 41.82 people for 100 thousand population. Mortality among men surpasses mortality among women for T1D (2.11 men/1.76 women), whereas the opposite was observed for T2D (58.79 women/21.81 men). Life expectancy after a diagnosis of sugar diabetes is ma...

Background: Diabetic nephropathy is leading cause of end-stage renal disease (ESRD), which requires dialysis or a transplant. Progression of diabetic nephropathy (DN) leads to development of chronic renal failure (CRF).Material and methods: Data for 124 554 DM patients who live in Moscow region (MR) is in the MR DM register for 2004. The number of T1D- 8747, T2D patients is 115, 534. These registers only contain information about registered cases of DN.<...

Graves’ disease (GD) and thyroid-associated ophthalmopathy (TAO) are often observed together. In purpose to elucidate the pathogenetic relationships between these two autoimmune disorders we investigated profile of different autoantibodies in patients with GD without TAO (n=38, group 1), GD with TAO (n=40, group 2), and in healthy people (n=124, control group). Autoantibodies to thyroid gland, eye muscle cell membranes (Ab-EMCM) and skin fibroblasts w...

Introduction: Globally, the main cause of mortality of type 1 diabetes (T1D) is lack insulin access. There is minimal data of health outcomes for T1D in low-middle-income countries (LMICs) in South-East Asia (SEA) where government funding of insulin and blood glucose monitoring kits either do not exist or is limited. Action4Diabetes (A4D) is a non-government organisation (NGO) initiated in 2016 and supports children and young people (CYP) with T1D in five countries -Laos, Mala...

The primary aim of this study, the largest European, single evaluation, observational trial to date, was to evaluate the impact of acromegaly on health-related quality of life (HRQoL) in patients with biochemically documented active disease, receiving Sandostatin® LAR® at a dose prescribed by their physician for at least 3 months. Secondary objectives were to investigate the relationships between HRQoL and subpopulations based on exploratory var...