Searchable abstracts of presentations at key conferences in endocrinology

ea0012p36 | Diabetes, metabolism and cardiovascular | SFE2006

The effects of Sclerocarya birrea [(a. rich.) hochst.] [Anacardiaceae] stem-bark aqueous extract on blood glucose, kidney and cardiovascular function in rats

Musabayane CT , Gondwe M , Kamadyaapa DR , Moodley K , Ojewole JAO

Available evidence suggests that Sclerocarya birrea stem-bark extract (SBE) which possesses hypoglycaemic activity may be useful in the treatment and management of diabetes mellitus. Since diabetes is associated with cardiovascular and kidney complications, we investigated the influence of SBE on blood glucose, blood pressure and renal function in some experimental animal paradigms. For OGTT tests, separate groups (n=6 in each group) of non-diabetic and streptozo...

ea0008p27 | Diabetes, metabolism and cardiovascular | SFE2004

EFFECTS OF SYZYGIUM (i) CORDATUM (i) LEAF EXTRACT ON PLASMA GLUCOSE AND HEPATIC GLYCOGEN IN STREPTOZOTOCIN-INDUCED DIABETIC RATS

Musabayane CT , Mahlalela N , Shode FO , Ojewole JAO

The hypoglycaemic effect of Syzygium (i) cordatum (i) leaf extract was studied in non-diabetic and streptozotocin (STZ)-induced diabetic rats. The crude was subjected to column chromatography and spectroscopic analysis. Non-diabetic and STZ-diabetic rats were orally administered glucose (1.4 g.100 kg-1 (super -1) body weight) followed by extract (6 mg.100-1g (super -1) body weight). Weekly plasma glucose and terminal hepatic glycogen concentrations were recorded in control STZ...