Endocrine Abstracts

Introduction: Resistance to thyroid hormone beta is a genetic disease defined by impaired sensitivity of target tissue to thyroid hormone caused by mutation of thyroid hormone receptor beta gene, appearing with an incidence of 1/40,000. The characteristic biochemical profile of resistance to thyroid hormone is elevated serum thyroid hormone level and inappropriate serum level of thyrotropin (TSH) which is normal or elevated. Clinical picture is variable ranging from asymptomat...

Objectives: Ultrasound-guided fine needle aspiration biopsy (FNAB) is a commonly performed diagnostic procedure for evaluation of thyroid nodules. The Bethesda System for Reporting Thyroid Cytopathology comprises six categories. Bethesda categories I and III present a challenge for deciding on further diagnostic and therapeutic procedures. Category I includes non-diagnostic or unsatisfactory results that may be due to both aspiration of cystic material from simple cysts or asp...