Searchable abstracts of presentations at key conferences in endocrinology

ea0090p767 | Thyroid | ECE2023

Analysis of curative effect after 131I treatment of familial differentiated thyroid cancer

Ji Yanhui , Sun Danyang , Zheng Wei

Objective: To analysis the clinical pathological characteristics and 131I curative responses of familial differentiated thyroid cancer(FDTC) and sporadic differentiated thyroid cancer(SDTC).Methods: A total of 112 FDTC patients(79 females, 33males, age(41.3±15.6)) and 1000 SDTC (658 females, 342males, (44.2±13.9)) who underwent 131I therapy in Department of Nuclear Medicine in our hospital between January 2011 and July 2021 we...

ea0090p654 | Endocrine-related Cancer | ECE2023

Intermediate-risk Differentiated Thyroid Cancer with Stimulated Thyroglobulin or N1b Needs High Adjuvant Radioactive Iodine Dose

Li Xue , Zheng Wei , Ji Yanhui , Sun Danyang , Wang Xuan

Background: There are no definite recommendations on the optimal dosage of initiating adjuvant radioactive iodine (RAI) therapy for intermediate-risk differentiated thyroid cancer (DTC) patients in current relevant guideline. This study aimed to investigate the response of intermediate-risk DTC patients with a low (3.7GBq) or high RAI dose (5.55GBq).Methods: Propensity score matching was performed to control for baseline characteristics. A total of 476 p...

ea0090p225 | Thyroid | ECE2023

Clinical Characteristics of Differentiated Thyroid Carcinoma with Obesity and Glucose Metabolism

Wang Xuan , Zheng Wei , Li Xue , Sun Danyang , Ji Yanhui

Objective: To explore the association between body mass index (BMI) and plasma glucose level with pathological features and clinical outcomes of differentiated thyroid cancer (DTC).Methods: Clinical data of 1264 consecutive DTC patients treated with total thyroidectomy and enrolled at the time of the first 131I treatment from April 2016 to July 2020. The clinicopathological findings were compared in the groups were categorized according to BMI...

ea0090p216 | Thyroid | ECE2023

UPLC-Q-TOF/MS-based metabolomics explored the metabolic mechanisms of thyroid cancer in different background

Sun Danyang , Li Xue , Wang Xuan , Ji Yanhui , Meng Zhaowei , Zheng Wei

Thyroid papillary carcinoma (PTC) is the most common endocrine tumor, HashimotoÂ’s thyroiditis (HT) is considered to be closely related to PTC pathogenesis, but their relationship still needs verification and exploration. Aim of the study. To analyze the differences and similarities of the metabolic mechanism of thyroid papillary carcinoma in normal and HT background, and to explore the relationship between HT and PTC. The Ultra performance liquid chromatography-q...