ea0081p66 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022
Jeong Jae Yeop
, Choi Sung-E
, Song Min Woo
, Ho Park Suck
, Kang Yup
, Ho Kim Tae
, Ahn So-Yeon
, Jin Kim Hae
, jin Han Seung
, Jeon Ja Young
, Lee Nami
, Jung Kim Dae
, Lee Kwan-Woo
Aim/hypotheses: Ectopic lipid accumulation in the heart contributes to the abnormal function of the heart and to the death of cardiomyocytes. Saturated FFA is one of the most important causes of death in cardiomyocytes. Although empagliflozin has been reported to be beneficial for people with diabetic complications and/or CVD, it has not been confirmed as to how it affects cardiomyocytes death by FFA. This study was designed to evaluate the protective effects of SGLT2 inhibito...