ea0070aep1082 | Hot topics (including COVID-19) | ECE2020
Juul Kildemoes Rasmus
, Viig Overgaard Rune
, Højby Rasmussen Michael
In patients with adult growth hormone deficiency (AGHD), the dose of growth hormone (GH) replacement is individualised based on clinical outcome, insulin-like growth factor-I (IGF-I) levels and adverse reactions. The aim of this analysis was to characterise dose–IGFI–response for somapacitan, a long-acting reversible albumin-binding GH derivative, and to derive expected IGF-I levels for various starting doses. Somapacitan dose–IGF-I–response analysis wa...