ea0029p238 | Calcium & Vitamin D metabolism | ICEECE2012
Kanai G.
, Sawada K.
Introduction: Two major assay systems have been used for evaluation of parathyroid hormone (PTH) secretion. Whole PTH (wPTH) recognizes full-length 84 amino acid residues [PTH(184)], and Intact PTH (iPTH) recognizes NH2-truncated forms, such as PTH(784), in addition to PTH(184). Patients with chronic renal failure have increased amount of PTH(784) in circulations, so that the ratio of wPTH/iPTH indicates 0.7 or below usually. On the other hand, chromogr...