Searchable abstracts of presentations at key conferences in endocrinology

ea0072p11 | (1) | UKINETS2020

The discontinuation of interferon-alfa for the treatment of metastatic NET: A case amongst many of poorer patient outcomes?

Fenn Ricky , Pawsey Alexander , Kapur Gaurav

Interferon alfa-2a was discontinued in June 2020. Here we present a case of an unfortunate patient for whom this change has dramatically impacted the course of her illness. A 64-year-old woman initially presented in 2007 with refractory hypertension and was found to have a phaeochromocytoma which was resected. Metastatic recurrence of her disease in the liver and vertebrae was confirmed by CT/MRI in 2014 following rising catecholamines on monitoring. Her MIBG scan in early 201...

ea0086p196 | Endocrine Cancer and Late Effects | SFEBES2022

Prevalence of vitamin B12 deficiency in neuroendocrine tumour-Single Centre Experience

Tun Yee LaiLai , Myint Han Myint , Kapur Gaurav , Swe Myint Khin

Background: Neuroendocrine tumours (NET) are heterogenous group of tumours commonly arising from Gastro-pancreatic (GI) and pulmonary origins. Combination of bowel resection, disease related diarrhoea and somatostatin analogue therapy (SSA) can contribute to vitamin B12 deficiency (B12D). International guidelines do not suggest routine screening. Total serum cobalamin (B12) level can be falsely normal in patients with B12D. Cells take up B12 in the form of Holotranscobalamin (...

ea0046p17 | (1) | UKINETS2016

UK Phase IV, Observational study to assess Quality of Life in patients (pts) with pancreatic neuroendocrine tumours (pNETs) receiving treatment with Everolimus: The “Real-World” OBLIQUE Study

Ramage John , Punia Pankaj , Olusola Faluyi , Frilling Andrea , Meyer Tim , Kapur Gaurav , Cave Judith , Wadsley Johnathan , Cummins Sebastian , Farrugia David , Starling Naureen , Wall Lucy , Saharan Ruby , Valle Juan

Background: Everolimus, a mammalian target of rapamycin inhibitor, is licensed for use in adult pts with advanced well-differentiated pNETs in the UK. Limited Health-Related Quality-of-Life (HrQOL) data are available for everolimus therapy in these pts.Methods: This prospective study assessed changes in HrQoL (by monthly patient-reported EORTC QLQ-C30, -G.I.NET21 and EQ-5D questionnaires), in pts with pNETs during the first 6 months (mo) of treatment wit...