Searchable abstracts of presentations at key conferences in endocrinology

ea0056p586 | Obesity | ECE2018

A newly inflammatory marker in overweight patients: triggering receptor expressed on myeloid cellls-1

Cifci Aydin , Durmaz Senay Arikan , Oklu Kubra , Katar Didem , Boyunaga Hakan , Badem Nermin Dindar

Introduction and aims: Triggering receptor expressed on myeloid cells 1 (TREM-1) is secreted by macrophage and neutrophils in adipose tissue to released pro-inflammatory chemokines and cytokines. TREM-1 activate Janus kinase 2 (JAK2), protein kinase B (PKB/AKT) and extracellular signal related kinase (ERK1/2) pathways and upregulate the expression of genes involved in the inflammatory response. We aimed to indicate associations with serum TREM-1 levels, total sulfhydryl (SH) a...