Searchable abstracts of presentations at key conferences in endocrinology

ea0038p119 | Clinical practice/governance and case reports | SFEBES2015

An audit in to the investigation of spontaneous hypoglycaemia: experience at a tertiary centre

Katreddy Mahesh , Varadhan Laks , Varughese George , Edavalath Mahamood , Nayak Ananth

Background: Adult spontaneous hypoglycaemia in non-diabetic patients is not a diagnosis per se but a manifestation of a disease and is often a diagnostic challenge. Although rare, it’s important to exclude endogenous hyperinsulinemia, because treatment can be curative. The aim of our audit was to assess the usefulness of various investigations done for spontaneous hypoglycaemia in diagnosing Insulinoma.Methods: Data on 98 non-diabetic patie...

ea0038p245 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2015

Obstructive sleep apnoea and bariatric surgery: the need for more universal screening and post-operative follow up

Martinou Chrysiis , Nayak Ullal , Katreddy Mahesh , Varughese George , Varadhan Lakshminarayanan

Aim: Bariatric surgery can provide significant weight loss but a complete resolution obstructive sleep apnoea (OSA) cannot be predicted. The aim of our audit was to assess the prevalence of OSA in bariatric clinics and outcomes after malabsorptive bariatric surgery.Methods: Retrospective observational analysis was performed on patients who had undergone bariatric surgery (laparoscopic gastric bypass and sleeve gastrectomy) and completed a minimum of 6 mo...

ea0022p235 | Clinical case reports and clinical practice | ECE2010

Carbimazole induced neutropenia: are we too cautious?

Smith Robert , Saraf Sanjay , Madhusudana Kattepura , Katreddy Mahesh , Ashawesh Khaled

Carbimazole is a commonly used antithyroid drug with a rare but potentially life-threatening side effect of agranulocytosis. We present a case of a 47-year-old lady who was diagnosed with hyperthyroidism four years previously and treated with carbimazole despite persistent neutropenia.At diagnosis the patient had clinical features of hyperthyroidism and thyroid function test (TFT) showed free T4 40.8 pmol/l (10.6–21.0), free T3...

ea0022p236 | Clinical case reports and clinical practice | ECE2010

Carbimazole pseudo-resistance: two case reports

Madhusudana Kattepura , Saraf Sanjay , Smith Robert , Katreddy Mahesh , Ashawesh Khaled

Introduction: Weight gain following treatment of hyperthyroidism is well recognised. This may lead to compliance problems both in patients with/without eating disorders and subsequent failure of therapy. We describe two cases where this was successfully managed with supervised in-patient therapy.Case 1: A 30-year-old overweight lady was diagnosed with Grave’s disease following childbirth. Thyroid function test (TFT) at initiation of treatment showed...

ea0059p047 | Bone and calcium | SFEBES2018

Clinical efficacy of cinacalcet in primary hyperparathyroidism in reducing calcium and admission avoidance

Varadhan Lakshminarayanan , Nayak Ullal Ananth , Katreddy Mahesh , Cooper Julie , Varughese George

Aim: Cinacalcet is a useful treatment option in primary hyperparathyroidism (PHPT) who are managed conservatively; however there are licensing issues and challenges for prescribing in primary care. The aim of our study was to assess the efficacy of cinacalcet treatment in PHPT and benefit of admission avoidance.Methods: Data on patients treated with cinacalcet for PHPT were analysed. PTH, adjusted calcium and vitamin D at initiation, calcium at 6 and 12 ...

ea0034p141 | Clinical practice/governance and case reports | SFEBES2014

Granulomatosis with polyangiitis presenting as a pituitary lesion

Christou Louise , Katreddy Mahesh , Dutta Shouma , Kamath Sanjeet , Shaw Simon , Jose Biju

Granulomatosis with polyangiitis (GPA), previously known as Wegener’s granulomatosis, is a rare heterogeneous vasculitic disease characterised by necrotising granulomatous inflammation typically affecting lungs and kidneys. GPA affecting pituitary is rare and usually results in posterior pituitary involvement causing diabetes insipidus. We describe a case of GPA, presenting with pituitary involvement causing headaches and anterior pituitary hormone deficiencies.<p cla...