ea0034p333 | Reproduction | SFEBES2014
Tremaine Tina
, Khalid Mohammed
, Wathes Claire
, Fouladi-Nashta Ali
Successful embryo implantation requires changes in endometrial gene expression of biomarkers which contribute to uterine receptivity to facilitate blastocyst attachment. Osteopontin (OPN), expressed at the maternal–foetal interface may facilitate implantation in processes, such as cell adhesion, migration and angiogenesis which require OPN signalling via CD44 and integrin receptors. As coordinate expression of OPN and receptors is shown to be cycle-dependent and up-regula...