Searchable abstracts of presentations at key conferences in endocrinology

ea0099p462 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Glycemic control in patients with prediabetes acutely improves serum nlrp3 inflammasome and associated interleukins post-lifestyle modification

Alfadul Hend , Al-Daghri Nasser , Sabico Shaun , Khattak Malak , Clerici Mario

Background: Prediabetes (PD) is a significant risk factor diabetes mellitus (DM) and as such, behavioral interventions are the primary management for PD. High blood glucose levels alter circulating NLRP3 inflammasome complex activity and correlated interleukins (ILs). There is limited data available on the activity of NLRP3 inflammasome and ILs in sera of patients with PD that may or may have not developed DM. This interventional study assessed the effects of NLRP3 inflammasom...