Searchable abstracts of presentations at key conferences in endocrinology

ea0028oc3.5 | Obesity, thyroid and Addison's disease | SFEBES2012

Steroidogenic function following B lymphocyte depletion therapy in new onset autoimmune Addison’s disease

Pearce Simon , Mitchell Anna , Bennett Stuart , King Philip , Chandran Sukesh , Nag Sath , Chen Shu , Furmaniak Jadwiga , Isaacs John , Vaidya Bijay

Background: A diagnosis of AddisonÂ’s disease means lifelong dependence on daily glucocorticoid and mineralocorticoid therapy and is associated with increased morbidity and mortality, as well as a risk of unexpected adrenal crisis. We wished to explore whether immunomodulatory therapy at an early stage of autoimmune AddisonÂ’s disease could lead to preservation or improvement in adrenal steroidogenic function.Design: We conducted an open-label, p...