Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep1035 | Hot topics (including COVID-19) | ECE2020

Polygenic risk scorecaptures 11% of of type 2 diabetes variability in latvian population

Pečulis Raitis , Reščenko Raimonds , Pīrāgs Valdis , Konrāde Ilze , Kloviņš Jānis

Type 2 diabetes (T2D) is a multi factorial disease with increased prevalence globally. The risk of developing T2D is determined by the interaction of genetic and environmental factors. Over the decades of research, hundreds of T2D genetic susceptibility markers (mostly single nucleotide polymorphisms or SNP) have been discovered. Yet generally their contribution to increased T2D risk is small and have negligible value in clinical practice to aid T2D treatment, categorize patie...