Endocrine Abstracts

Introduction: Polycystic ovary syndrome (PCOS) is a common endocrinopathy that affects 5–10% of women of reproductive age. It is now recognized as not only a reproductive but also a metabolic disorder with co-morbidities, such as; diabetes, dyslipidemia, hypertension, etc. All these metabolic abnormalities predispose women with PCOS to atherosclerosis. Plasma viscosity is a major determinant of blood flow in microcirculation. Preliminary data indicate that elevated plasma...

Objective: Platelet activation is a recently recognized characteristic of prolactin, which functions through the potentiation of ADP-induced P-selectin expression on platelets. Studies in hyperprolactinemic patients demonstrated atherosclerotic disorders related to insulin resistance; convenient milieus for platelet activation. To investigate the association between hyperprolactinemia and platelet activation related to P-selectin expression, we studied on hyperprolactinemic an...