Searchable abstracts of presentations at key conferences in endocrinology

ea0014p192 | (1) | ECE2007

Pioglitazone modifies the effects of growth hormone on lipolysis and insulin sensitivity

Krag Morten B , Nielsen Søren , Guo ZengKui , Pedersen Steen B , Schmitz Ole , Christiansen Jens S , Jørgensen Jens OL

Context: Thiazolidiones (TZD) improves insulin sensitivity in type 2 diabetes via effects on fat metabolism, whereas growth hormone (GH) stimulates lipolysis and induces insulin resistance.Objective: To evaluate the effects of TZD on fat metabolism and insulin sensitivity in GH-treated GH deficient (GHD) patients.Design: Randomized, placebo-controlled, double-blind parallel-group study including 20 GHD patients on continued GH repl...