ea0081p245 | Late-Breaking | ECE2022
Doyle Luc
, Okiro Julie
, Sarwani Aysha
, Troy Michael
, Ansari Yousef
, O′Donoghue Darragh
, Lappin David
, Mcevoy John
, O'Shea Paula
, Ferguson John
, Conall Dennedy Michael
Rationale: The Aldosterone:Renin ratio (ARR) is commonly used for patients fulfilling screening criteria for primary hyperaldosteronism (PA), followed by confirmatory testing. Reference intervals for interpretation of the ARR vary in accordance with local population and assay 1. While ARR provides high sensitivity for PA, this is compromised by low specificity, further compounded by medication interference. However, additional variables may improve the specificity of ARR as a ...