Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep704 | Obesity | ECE2017

Elevated serum adiponectin in Alzheimer’s disease as neuroprotective strategy

Letra Liliana , Rodrigues Tiago , Matafome Paulo , Duro Diana , Lemos Raquel , Patricio Miguel , Castelo-Branco Miguel , Baldeiras Ines , Seica Raquel , Santana Isabel

Background: Several studies have highlighted the contribution of adipose tissue dysfunction to the development and progression of Alzheimer’s Disease (AD), which may depend on alterations in adipokine secretion. Leptin and adiponectin are the most abundant adipokines in circulation, with recognized systemic effects, but also able to cross the blood-brain barrier and influence cognitive-related structures, such as the hippocampus.Objective: To determ...