Endocrine Abstracts

In the central nervous system, the opioid and non-opioid transmitter system jointly compete with multiple pathophysiological processes. The in vitro neuronal model of rat (Wistar) caudate putamen and reverse transcription-poly-merase chain reaction were used to examine the effects of neurotensin and/or morphine on the expression of mu or delt-opioid receptor mRNA. In the present study neurotensin (10 nmol/l) promoted but morphine (0.001 mmol/l) reduced mu or delt-opioid...

Background: Primary aldosteronism (PA) is mainly caused by unilateral (unilateral PA) or bilateral aldosterone-producing lesions of adrenals (bilateral PA). Accumulating findings suggest distinct metabolic profiles between patients with unilateral and bilateral PA. However, the link between the metabolic features and histopathologic findings of adrenals from patients with PA remains largely unknown.Objective: To characterize metabolic profiles with a foc...