Searchable abstracts of presentations at key conferences in endocrinology

ea0060p27 | (1) | UKINETS2018

Unmasking ectopic ACTH secretion and changing functionality of a pulmonary neuroendocrine tumour with carcinoid syndrome

Wijesinghe Achini , Lorenz Eleanor , Munir Alia

Pulmonary neuroendocrine tumors (NET) are well recognized, but quite an uncommon group of disorders to cause ectopic Cushing’s syndrome. Pulmonary NETs have also undergone a change in treatment paradigms. We present a 62 year old female with incidentally detected left lower lobe lung nodule with biopsy proven well differentiated NET with ki67 index of 5–10% in 2011. She had a metachronous slow growing left sided renal tumor (hypernephroma), long standing type 2 diabe...

ea0062p09 | Poster Presentations | EU2019

Chronic diarrhoea - a rare endocrine cause

Pillai Sanesh , Munir Alia , Lorenz Eleanor , Wadsley John

Case history: A 59-year-old male presented to gastroenterology with a two years of high volume persistent watery diarrhoea. He gave a past medical history of poorly controlled, insulin treated diabetes mellitus present for 8 years. He reported abdominal pain and diarrhoea that persisted despite fasting. A colonoscopy with biopsy were reported as normal. Diarrhoea, malaise, fatigue and weight loss persisted.Investigations: Stool culture and faecal elastas...

ea0063p843 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

Efficacy of somatostatin analogues in managing hypercalcaemia due to PTHrP in a well differentiated metastatic pancreatic neuroendocrine tumour and discussion of modern treatment options: A clinical case

Uchambally Manjima , Munir Alia , Wadsley Jonathan , Lorenz Eleanor

Pancreatic neuroendocrine tumours are rare with an incidence of 5 per million. Of these tumours, 75% maybe hormonally functioning. They carry a better prognosis than adenocarcinoma of the pancreas. Parathyroid Hormone related peptide hypersecretion in PNETs is uncommon and is solely associated with metastatic PNETs. 31 cases are reported of PTH-rPoma in the literature. Here we describe a novel case presenting with cough. A previously well 56-year-old female presented to the ac...

ea0038p103 | Clinical practice/governance and case reports | SFEBES2015

Splenunculi masquerading as neuroendocrine tumours

Walkinshaw Emma , Lorenz Eleanor , Blakeborough Tony , Munir Alia

Splenunculi or accessory spleens are congenital foci of normal splenic tissue that are separate from the main body of the spleen. They are common, with a prevalence of 16% on contrast-enhanced abdominal CT, and present in 10–30% of post mortem examinations. They are benign, and important to recognise to avoid unnecessary investigations and surgery for suspected malignancies.Splenunculi are usually asymptomatic and found incidentally. Typically on CT...

ea0046p35 | (1) | UKINETS2016

Cardiac metastases from ileal NETs

Liyanarachchi Kamani , Amarawardena Maheshi , Lorenz Eleanor , Newell-Price John , Munir Alia

Background: Intracardiac metastasis of carcinoid tumours are rare (incidence 2–4%). Their presence without carcinoid valvulopathy or carcinoid syndrome is unusual.Case Discussions: A 70 year old male presented with abdominal pain. CT imaging revealed a small intestinal tumor with liver and mesenteric metastasis. Biopsy showed a neuroendocrine tumour (NET). Clinical and biochemical evidence of functionality was absent. He underwent definitive small b...