Endocrine Abstracts

Pulmonary neuroendocrine tumors (NET) are well recognized, but quite an uncommon group of disorders to cause ectopic Cushing’s syndrome. Pulmonary NETs have also undergone a change in treatment paradigms. We present a 62 year old female with incidentally detected left lower lobe lung nodule with biopsy proven well differentiated NET with ki67 index of 5–10% in 2011. She had a metachronous slow growing left sided renal tumor (hypernephroma), long standing type 2 diabe...

Case history: A 59-year-old male presented to gastroenterology with a two years of high volume persistent watery diarrhoea. He gave a past medical history of poorly controlled, insulin treated diabetes mellitus present for 8 years. He reported abdominal pain and diarrhoea that persisted despite fasting. A colonoscopy with biopsy were reported as normal. Diarrhoea, malaise, fatigue and weight loss persisted.Investigations: Stool culture and faecal elastas...

Pancreatic neuroendocrine tumours are rare with an incidence of 5 per million. Of these tumours, 75% maybe hormonally functioning. They carry a better prognosis than adenocarcinoma of the pancreas. Parathyroid Hormone related peptide hypersecretion in PNETs is uncommon and is solely associated with metastatic PNETs. 31 cases are reported of PTH-rPoma in the literature. Here we describe a novel case presenting with cough. A previously well 56-year-old female presented to the ac...

Splenunculi or accessory spleens are congenital foci of normal splenic tissue that are separate from the main body of the spleen. They are common, with a prevalence of 16% on contrast-enhanced abdominal CT, and present in 10–30% of post mortem examinations. They are benign, and important to recognise to avoid unnecessary investigations and surgery for suspected malignancies.Splenunculi are usually asymptomatic and found incidentally. Typically on CT...

Background: Intracardiac metastasis of carcinoid tumours are rare (incidence 2–4%). Their presence without carcinoid valvulopathy or carcinoid syndrome is unusual.Case Discussions: A 70 year old male presented with abdominal pain. CT imaging revealed a small intestinal tumor with liver and mesenteric metastasis. Biopsy showed a neuroendocrine tumour (NET). Clinical and biochemical evidence of functionality was absent. He underwent definitive small b...