ea0020p444 | Obesity and Metabolism | ECE2009
, de Jong Jos
, van Sorge Adriaan
, Telting Darryl
, de Boer Hans
Introduction: Hypogonadotropic hypogonadism is frequently observed in morbidly obese men, due to aromatase-dependent conversion of androgens to estrogens in adipocytes. The clinical impact of this sex hormone imbalance is not known.Aim: To evaluate the clinical effects of aromatase inhibition in obesity-related hypogonadotropic hypogonadism.Methods: Double-blind, placebo-controlled trial for 6 months in severely obese men (BMI >...