Endocrine Abstracts

Central vasopressin facilitates social recognition and modulates numerous complex social behaviours in mammals, including parental behaviour, aggression, affiliation and pair-bonding. In rodents, social interactions are primarily mediated by the exchange of olfactory information, and there is evidence that vasopressin signalling is important in brain areas where olfactory information is processed. We recently discovered that the rat olfactory bulb (OB)1 and the ante...

Vasopressin acts through G protein-coupled receptors on the cardiovascular and renal system to induce vasoconstriction and antidiuresis. Vasopressin also has important functions within the CNS influencing cognition, olfaction and a range of complex social interactions and behaviours. In addition, vasopressin has been reported in the mammalian retina and here we investigated the location and expression of vasopressin and vasopressin receptors (V1a, V1b, and V2) in the rat retin...

Introduction: Intramuscular Testosterone Undecanoate (TU, Nebido®) has become available in November 2004 in Europe for the treatment of male hypogonadism. Continuous physiological hormone replacement is necessary for transgender patients, both prior to the gender adjustment operation and for the remainder of the individual’s lifetime. The administration of long-acting TU therefore stood to reason as part of cross-gender testosterone therapy for female-to-m...