Searchable abstracts of presentations at key conferences in endocrinology

ea0014p207 | (1) | ECE2007

Association of estrogen receptor-alpha gene polymorphisms with cerebrovascular disease in patients with metabolic syndrome

Xita Nektaria , Markoula Sophia , Lazaros Leandros , Kyritsis Athanasios , Georgiou Ioannis , Tsatsoulis Agathocles

Introduction: The vascular protective effects of estrogens are known to be mediated by their binding to specific estrogen receptors (ER). However, the significance of genetic variations of the ER in vascular diseases has not been reported. We have examined the association between stroke and PvuII and XbaI polymorphisms of the estrogen receptor-alpha gene in patients with metabolic syndrome.Methods and subjects: The study population consisted by 84 male a...