Endocrine Abstracts

Background: Аgrowing body of evidence suggests that type 2 diabetes mellitus (T2DM) may contribute to the the development and deterioration of heart failure (HF) with either reduced or preserved ejection fraction. On the other hand, diabetic kidney disease (DKD) is associated with a high risk and worsе outcomes of HF. However, the relationship between DKD and various types of HF hasn’t been fully investigated. The aim of this study was to assess the association b...

Background: Chronic kidney disease develops in approximately 40% of patients with type 2 diabetes mellitus (T2DM) and significantly increases the risk of mortality and cardiovascular morbidity. Finerenone, a novel nonsteroidal mineralocorticoid receptor antagonist, has demonstrated a significant impact on renal function by reducing proteinuria and preserving glomerular filtration rate in patients with chronic kidney disease. However, the influence of finerenone on kidney funct...