ea0032p644 | Male reproduction | ECE2013
Roelofs Maarke J E
, Dankers Anita C A
, Piersma Aldert H
, Russel Frans G M
, van den Berg Martin
, Masereeuw Rosalinde
, van Duursen Majorie B M
Efflux transporters in the blood–testis barrier (BTB) prevent entry and accumulation of xenobiotics in testis but are also involved in local transport of steroid hormones. Among these are the ATP-binding cassette (ABC) transporters, P-glycoprotein (P-gp/ABCB1) and multidrug resistance proteins 1 (MRP1/ABCC1) and 4 (MRP4/ABCC4). Here, we studied the interaction of suggested endocrine disruptors (EDCs) bisphenol A (BPA), tetrabromobisphenol A (TBBPA), bis(...