Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep1180 | Thyroid | ECE2024

Heterogeneous clinical outcomes in two separate cases of advanced differentiated thyroid cancers

Mazza Massimiliano , Parazzoli Chiara , Favero Vittoria , Emanuela Carioni , Falchetti Alberto , Grossrubatscher Erika , Zampetti Bendetta , Chiodini Iacopo , Dalino Ciaramella Paolo

Background: Among differentiated thyroid cancers, follicular thyroid carcinoma (FTC) is the second most prevalent, representing 10-15% of cases. Histopathological features, tumour size, multifocality, presence of lymphnode metastasis at diagnosis are the most impacting features affecting clinical outcome. Tumour microenvironment (TME) may have an important ancillary role for disease progression. We present two cases of FTC with biochemical and structural persistence of disease...

ea0070aep578 | Pituitary and Neuroendocrinology | ECE2020

Association between sagittal spine imbalance and radiological vertebral fractures in acromegaly: Does it reflect a pathophysiological link?

Cellini Miriam , Biamonte Emilia , Trenti Nicoletta , Mazza Massimiliano , Milani Davide , Ferrante Emanuele , Lavezzi Elisabetta , Mantovani Giovanna , Arosio Maura , Fornari Maurizio , Balzarini Luca , Lania Andrea , Mazziotti Gherardo

Chronic exposure to GH hypersecretion may alter the physiological balance of the spine through inducing degeneration of intervertebral discs and impaired trophism of facet joints. Moreover, GH in excess may also cause profound deterioration in bone microstructure with consequent increase in risk of fragility vertebral fractures (VFs). In this cross-sectional study,we evaluated for the first time in acromegaly the association between spine imbalance and VFs. Thirty-eight patien...