Searchable abstracts of presentations at key conferences in endocrinology

ea0014p475 | (1) | ECE2007

Six months physiological DHEA substitution in female adrenal failure: impact on quality of life and sexual parameters.

Christiansen Jens J , Mehlsen Mimi , Geraldi Anna Maria , Gravholt Claus , Jørgensen Jens O , Christiansen Jens S

Female adrenal failure involves impaired DHEA secretion and very low circulating androgens. To address the impact of a daily physiological substitution dose of capsule DHEA 50 mg on quality of life and sexual parameters, we performed a 6 month trial in a randomised, crossover and placebo controlled design. The trial was approved by the local ethical committee and conducted according to GCP guidelines. Ten patients were enrolled. Seven patients reported seborrhoic side effects ...