ea0028oc2.3 | Reproduction and bone | SFEBES2012
Milton Nathaniel
Kisspeptin is a 54 amino acid peptide that stimulates Gonadotrophin-Releasing-Hormone (GnRH) release from the hypothalamus and consequently activates the Hypothalamic-Pituitary-Gonadal (HPG) axis. Recent studies have suggested that Kisspeptin also binds and activates Neuropeptide FF (NPFF) receptors. The C-terminal ten residues of Kisspeptin are capable of activation of both GnRH release and NPFF receptors. The aim of the current study was to determine which amino acids of Kis...