Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep240 | Bone & Osteoporosis | ECE2017

Trabecular bone score is negatively associated with bone resorbtion markers in patients with primary hyperparathyroidism

Grigorie Daniel , Ivan Mirela , Caragheorgheopol Andra , Paun Diana , Sucaliuc Alina

Objectives: Mean TBS (Trabecular Bone Score) values are generally lower in PHPT (primary hyperparathyroidism) patients than controls. The aim of this study was to assess TBS from spine DXA images in patients with PHPT and look at its correlates.Methods: This was a cross-sectional study conducted in an osteoporosis referral center. One hundred and thirty six patients with PHPT were selected from our database (2010–2016) if they had a valid LS DXA sca...

ea0022p91 | Bone/Calcium | ECE2010

Long-term follow-up of the changes in serum 25-hydroxivitamin D to oral treatment with vitamin D3 in patients with postmenopausal osteoporosis

Grigorie Daniel , Sucaliuc Alina , Ivan Mirela , Neacsu Elena , Diaconescu Alina

The oral dosing with cholecalciferol needed to achieve and maintain optimal serum concentration 25-hydroxyvitamin D (25OHD) is still controversial.This study reports on the efficacy of supplementation with oral vitamin D3 1000 U/day for 3–18 months on serum 25OHD levels in 87 ambulatory patients with postmenopausal osteoporosis (mean age 63.5 years). Serum 25OHD, parathyroid hormone (PTH), calcium (serum, urine), phosphate, alkaline phosphatase and ...

ea0063p686 | Pituitary and Neuroendocrinology 2 | ECE2019

Delayed psychotic episod in a patient with panhipopituitarism and central diabetes insipidus after craniopharyngioma removal

Lazar Diana-Georgiana , Oros Sabina Elena , Dumitrascu Anda , Dobrescu Mariana , Ivan Mirela , Grigorie Daniel

Introduction: Central diabetes insipidus is a rare disorder, characterized by a failure of the posterior pituitary to produce vasopressin that lead to hypotonic polyuria and polydipsia. Diabetes insipidus may be due to post-pituitary surgery, where sometimes the posterior lobe also has to be removed or damaged; other injury as fractures of the skull, trauma, infiltrative lesions, tumors/metastases, idiopathic or rare genetic causes. As the sensation of thirst is the key homeos...

ea0056p251 | Calcium & Vitamin D metabolism | ECE2018

Primary hyperparathyroidism-localisation studies’ sensitivity

Oros Sabina Elena , Gongu Robert Andrei , Diaconescu Laura Alina , Ivan Mirela , Grigorie Daniel , Gudovan Emilia , Dumitrascu Anda , Hortopan Dan , Goldstein Andrei

Primary hyperparathyroidism can be caused by adenoma, adenocarcinoma, parathyroid hyperplasia or ectopic parathyroid glands. The American Association of Endocrine Surgeons Guidelines for Definitive Management of Primary Hyperparathyroidism recommends imaging as a helping tool in locating the causative lesion rather than a must for diagnosis. Experienced surgeons rely on the intraoperative localisation of the lesion. Pre surgery localisation helps for a minimally invasive appro...