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Endocrine Abstracts

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ea0070aep1 | Adrenal and Cardiovascular Endocrinology | ECE2020

Residual corticosteroid production in autoimmune addison´s disease

Bjorvatn Saevik Åse , Åkerman Anna-Karin , Methlie Paal , Quinkler Marcus , Palmström Jörgensen Anders , Höybye Charlotte , Debowska Aleksandra J , Gunnar Nedrebø Bjørn , Lise Dahle Anne , Carlsen Siri , Tomkowicz Aneta , Therese Sollid Stina , Nermoen Ingrid , Grønning Kaja , Dahlqvist Per , Grimnes Guri , Skov Jakob , Finnes Trine , Valland Susanna F , Wahlberg Jeanette , Emblem Holte Synnøve , Simunkova Katerina , Kämpe Olle , Sverre Husebye Eystein , Bensing Sophie , Øksnes Marianne

Background: Previous research show that autoimmune adrenal insufficiency develops gradually over time and inexorably results in a total inability to produce adrenal steroids. However, growing evidence suggest that a few patients preserve some steroid producing capacity.Aim: To explore the frequency of residual cortisol production and possible clinical consequences in patients with autoimmune Addison´s disease (AAD).Material an...
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ea0073aep4 | Adrenal and Cardiovascular Endocrinology | ECE2021

Biomarkers of cardiovascular disease and inflammation in autoimmune addison’s disease with residual adrenocortical function

Åse Bjorvatn Sævik , Anna-Karin Åkerman , Methlie Paal , Quinkler Marcus , Anders Jørgensen , Charlotte Höybye , Debowska Aleksandra , Bjørn Gunnar Nedrebø , Dahle Anne Lise , Carlsen Siri , Tomkowicz Aneta , Synnøve Holte , Sollid Stina Therese , Nermoen Ingrid , Kaja Grønning , Dahlqvist Per , Grimnes Guri , Skov Jakob , Finnes Trine , Valland Susanna , Wahlberg Jeanette , Simunkova Katerina , Olle Kämpe , Husebye Eystein Sverre , Bensing Sophie , Marianne Øksnes

BackgroundResidual adrenocortical function (RAF) is present in one third of patients with autoimmune Addison’s disease (AAD), yet its clinical significance remains unknown.ObjectiveTo investigate if biomarker profiles of cardiovascular disease and inflammation are different in patients with AAD and RAF compared to patients without RAF and healthy controls.Material and methods<p...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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